Trintellix (vortioxetine)
Get a new prescription or refill for Trintellix online with a virtual consultation from a licensed psychiatric provider. Receive personalized care for major depressive disorder (MDD), covered by most major insurance plans.

What is Trintellix (vortioxetine)?
Trintellix (vortioxetine) is an antidepressant used to treat major depressive disorder (MDD). By targeting serotonin levels in the brain, it helps alleviate symptoms like persistent sadness, lack of interest in activities, and difficulty concentrating. With its unique mechanism of action, Trintellix also supports cognitive function, providing a well-rounded approach to managing depression.
What is Trintellix (vortioxetine) used for?
Trintellix (vortioxetine) is prescribed to help manage symptoms of major depressive disorder (MDD) by improving mood, cognitive function, and emotional well-being. It helps regulate serotonin levels in the brain to alleviate common symptoms associated with depression.
A Trintellix (vortioxetine) prescription can help relieve symptoms like:
- Persistent sadness or low mood
- Loss of interest in activities once enjoyed
- Difficulty concentrating or focusing
- Trouble making decisions
- Feelings of worthlessness or excessive guilt
- Fatigue or low energy
- Changes in appetite or weight
- Sleep disturbances (insomnia or oversleeping)
- Anxiety or restlessness
- Thoughts of self-harm or suicide
What are the side effects of Trintellix (vortioxetine)?
Trintellix (vortioxetine) can cause side effects, though they don’t affect everyone the same. Some of the more common side effects include nausea, dizziness, dry mouth, and changes in appetite. These tend to be mild and often improve as your body adapts to Trintellix. If they persist or become uncomfortable, your Talkspace provider can explore dosage adjustments or Trintellix alternatives.
Here’s how it works
Medications we prescribe online
Talkspace psychiatric providers diagnose and treat a wide variety of mental health conditions, including anxiety, depression, ADHD, and others. For some people, their treatment involves medication. Your provider can prescribe you medication if appropriate for your treatment.
Note: Talkspace does not prescribe controlled substances.
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Any questions?
Find trust-worthy answers on all things mental health at Talkspace.
Do you need a prescription for Trintellix (vortioxetine)?
Yes, Trintellix (vortioxetine) is only available with a prescription. A licensed healthcare provider must assess your symptoms to determine whether Trintellix is suitable for you.
Can I get Trintellix (vortioxetine) online?
Yes, after a virtual consultation with a licensed Talkspace provider, you can receive a prescription for Trintellix online to help manage your depression if they judge it appropriate.
Can I get Trintellix (vortioxetine) over the counter?
No, Trintellix is not available over the counter. You will need a prescription from a licensed healthcare provider.
What is Trintellix (vortioxetine) used to treat?
Trintellix (vortioxetine) is FDA-approved to treat major depressive disorder (MDD). By regulating serotonin levels in the brain, Trintellix helps improve mood, cognitive function, and overall emotional well-being.
What are the most common side effects of Trintellix (vortioxetine)?
Common side effects of Trintellix (vortioxetine) may include:
- Nausea
- Dizziness
- Constipation
- Vomiting
- Dry mouth
- Decreased appetite
These side effects are typically mild and tend to lessen as your body adjusts to the medication.
More serious side effects include:
- Increased risk of suicidal thoughts (especially in young adults)
- Serotonin syndrome (causes confusion, rapid heart rate, and high fever)
- Unusual bleeding or bruising
- Severe allergic reactions (swelling of the face, lips, or tongue)
- Eye pain
- Vision changes
- Seizures
If you experience any concerning side effects after taking Trintellix, contact your healthcare provider immediately.
Can I get a new prescription or prescription refill from Talkspace?
Yes, Talkspace providers can prescribe or refill Trintellix online after a consultation to ensure it’s the right treatment for your symptoms and needs.
Can I use my health insurance for online Trintellix (vortioxetine) prescriptions and refills?
Yes, Talkspace accepts most major insurance plans for online Trintellix prescriptions. However, coverage may vary, so be sure to confirm the details with your insurance provider.
How much does Trintellix (vortioxetine) cost?
The cost of Trintellix can vary depending on factors like insurance coverage, pharmacy pricing, and available discounts. Trintellix is not available in generic form at this time. Without insurance, the price may range from $300 to $500 per month. Manufacturer savings programs, discount cards, and coupons may help reduce the cost significantly.
How do you take Trintellix (vortioxetine)?
Take Trintellix exactly as prescribed by your doctor. It’s typically taken once daily and can be taken with or without food. Do not stop taking Trintellix suddenly, as this can lead to withdrawal symptoms. Also, try to avoid alcohol, as it may worsen side effects such as dizziness or drowsiness.
Why is Trintellix so good?
Trintellix works differently from some other antidepressants because it helps increase serotonin levels in two ways. It not only prevents serotonin from being absorbed too quickly, but it also helps boost serotonin activity directly in the brain. This unique approach can make it more effective for treating depression. Plus, unlike some other antidepressants, Trintellix is less likely to cause weight gain, which makes it a popular choice for people with major depressive disorder (MDD).
Disclaimer
Talk to your psychiatrist or healthcare professional about the possible risks and benefits associated with the above medications before starting treatment. It’s up to your psychiatric clinician’s professional judgment whether medication is prescribed. If you are in a life threatening situation – don’t use this site. Call +1 (800) 273-8255 or use these resources to get immediate help.







