Silenor (doxepin)
Access expert treatment online for depression, anxiety, or insomnia. Get a new prescription or renewal for Silenor (doxepin) online, covered by most major insurance plans.

What is Silenor (doxepin)?
Silenor is the brand name for the generic drug doxepin, an FDA-approved prescription medication designed to treat insomnia, anxiety, and depression. As a low-dose tricyclic antidepressant (TCA), Silenor works by regulating brain activity to improve sleep quality and promote emotional well-being. With personalized treatment, Silenor can help restore balance so you can feel better mentally and physically.
What is Silenor (doxepin) used for?
Silenor (doxepin) is primarily used to treat insomnia. In low doses, it’s specifically prescribed for sleep-related issues. In higher doses, Silenor is used to address symptoms of anxiety and depression. By influencing brain neurotransmitters, Silenor helps restore emotional balance and improves sleep quality, with the dosing adjusted based on individual needs and the condition being treated.
What are the side effects of Silenor (doxepin)?
Common side effects include:
- Dizziness
- Drowsiness
- Constipation
- Dry mouth
- Difficulty urinating
- Blurry vision
- Nausea or vomiting
- Sweating
- Change in taste
- Weight changes
- Blood pressure changes
While these side effects are usually mild, if you notice any severe reactions or experience symptoms like confusion, rapid heart rate, or severe drowsiness, contact your healthcare provider right away. Always follow your doctor’s instructions and report any unexpected changes in your health.
Here’s how it works
Medications we prescribe online
Talkspace psychiatric providers diagnose and treat a wide variety of mental health conditions, including anxiety, depression, ADHD, and others. For some people, their treatment involves medication. Your provider can prescribe you medication if appropriate for your treatment.
Note: Talkspace does not prescribe controlled substances.
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Any questions?
Find trust-worthy answers on all things mental health at Talkspace.
Do you need a prescription for Silenor (doxepin)?
Yes, Silenor (doxepin) requires a valid prescription from a licensed healthcare provider to ensure its safe and effective use for your condition.
Can I get Silenor (doxepin) online?
Yes, you can get a Silenor (doxepin) prescription online from Talkspace. After a thorough virtual consultation with a licensed psychiatrist and if Silenor is deemed appropriate for your symptoms, a prescription will be provided.
Can I get Silenor (doxepin) over the counter?
No, Silenor (doxepin) is not available over the counter (OTC). Due to the potential side effects and the need for proper medical supervision during treatment, it requires a prescription from a licensed healthcare provider.
What is Silenor (doxepin) used to treat?
In low doses, Silenor (doxepin) can treat insomnia. At higher doses, it’s also used to treat symptoms of anxiety and depression.
Can I get a new prescription or prescription refill from Talkspace?
Yes, Talkspace psychiatric providers are authorized to prescribe and refill medications like Silenor (doxepin) to address insomnia, anxiety, and depression, following a thorough virtual consultation.
Can I use my health insurance for online Silenor (doxepin) prescriptions and refills?
Yes, most major health insurance plans cover online prescriptions and refills for Silenor (doxepin). Talkspace accepts a variety of insurance providers for psychiatric care and medication management, including:
Be sure to check with your insurance plan to confirm specific coverage and details about the cost of your prescription.
How much does Silenor (doxepin) cost?
The price of Silenor (doxepin) can vary depending on your location, dosage, insurance coverage, and whether you opt for the brand-name or generic version. With the use of discount cards, the cost can be under $55 per month. Always consult your pharmacist or insurance provider for exact pricing.
How do you take Silenor (doxepin)?
Silenor (doxepin) is taken orally, typically once daily on an empty stomach. For insomnia, it is taken within 30 minutes of bedtime. For anxiety or depression, your doctor may prescribe a divided dose throughout the day, depending on your treatment plan.
What antidepressant is similar to Silenor (doxepin)?
Trazodone is a similar antidepressant to Silenor (doxepin). Both medications are commonly used to treat conditions like insomnia and depression.
While doxepin is often prescribed for its sedative effects to treat sleep problems, Trazodone is also commonly used to help with sleep while treating depressive symptoms. Each medication has unique properties, so it's important to consult with a healthcare provider to determine which option is best for your needs.
Disclaimer
Talk to your psychiatrist or healthcare professional about the possible risks and benefits associated with the above medications before starting treatment. It’s up to your psychiatric clinician’s professional judgment whether medication is prescribed. If you are in a life threatening situation – don’t use this site. Call +1 (800) 273-8255 or use these resources to get immediate help.







